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balf il 6  (R&D Systems)


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    R&D Systems balf il 6
    Balf Il 6, supplied by R&D Systems, used in various techniques. Bioz Stars score: 97/100, based on 1417 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/balf il 6/product/R&D Systems
    Average 97 stars, based on 1417 article reviews
    balf il 6 - by Bioz Stars, 2026-06
    97/100 stars

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    MUC5B −/− mice had more severe pulmonary inflammation. a HE staining in the control group. b – d HE staining in the smoke-exposed group: b emphysema; c neutrophil infiltration; d macrophage infiltration; e total leukocytes, f neutrophils and g macrophages in bronchoalveolar lavage fluid (BALF). h inflammation score. “*” indicates a significant difference; ***P < 0.001 compared with smoke-exposed MUC5B +/+ mice

    Journal: Respiratory Research

    Article Title: MUC5B regulates goblet cell differentiation and reduces inflammation in a murine COPD model

    doi: 10.1186/s12931-021-01920-8

    Figure Lengend Snippet: MUC5B −/− mice had more severe pulmonary inflammation. a HE staining in the control group. b – d HE staining in the smoke-exposed group: b emphysema; c neutrophil infiltration; d macrophage infiltration; e total leukocytes, f neutrophils and g macrophages in bronchoalveolar lavage fluid (BALF). h inflammation score. “*” indicates a significant difference; ***P < 0.001 compared with smoke-exposed MUC5B +/+ mice

    Article Snippet: The following mouse BALF ELISA kits were used: IL-6 (DY406-05, R&D), KC (DY453-05, R&D), TNF-α (DY410-05, R&D), MUC5AC (E-EL-M0799c, Elabscience), and MUC5B (E-EL-M0800c, Elabscience).

    Techniques: Staining, Control

    MUC5B −/− mice have decreased goblet cell differentiation. MUC5B +/+ mice (n = 15 per group) and MUC5B −/− mice (n = 10 per group). a PAS staining. b MUC5AC IHC. c PAS grade. d MUC5AC IHC score. e ELISA of MUC5AC in BAL fluid. f RT-qPCR of MUC5AC in lung tissue. g ELISA of MUC5B in BAL fluid. h RT-qPCR of MUC5B in lung tissue. “*” indicates a significant difference; ***P < 0.001, **P < 0.01 compared with smoke-exposed MUC5B +/+ mice

    Journal: Respiratory Research

    Article Title: MUC5B regulates goblet cell differentiation and reduces inflammation in a murine COPD model

    doi: 10.1186/s12931-021-01920-8

    Figure Lengend Snippet: MUC5B −/− mice have decreased goblet cell differentiation. MUC5B +/+ mice (n = 15 per group) and MUC5B −/− mice (n = 10 per group). a PAS staining. b MUC5AC IHC. c PAS grade. d MUC5AC IHC score. e ELISA of MUC5AC in BAL fluid. f RT-qPCR of MUC5AC in lung tissue. g ELISA of MUC5B in BAL fluid. h RT-qPCR of MUC5B in lung tissue. “*” indicates a significant difference; ***P < 0.001, **P < 0.01 compared with smoke-exposed MUC5B +/+ mice

    Article Snippet: The following mouse BALF ELISA kits were used: IL-6 (DY406-05, R&D), KC (DY453-05, R&D), TNF-α (DY410-05, R&D), MUC5AC (E-EL-M0799c, Elabscience), and MUC5B (E-EL-M0800c, Elabscience).

    Techniques: Cell Differentiation, Staining, Enzyme-linked Immunosorbent Assay, Quantitative RT-PCR

    MUC5B −/− mice have increased expression of macrophage-related inflammatory factors. MUC5B +/+ mice (n = 15 per group) and MUC5B −/− mice (n = 10 per group). a BAL fluid IL-6 ELISA. b BAL fluid TNF-α ELISA. c ERK1/2 western blot and grayscale analysis. d NF-κB western blot and grayscale analysis. “*” indicates a significant difference; ***P < 0.001, **P < 0.01 compared to smoke-exposed MUC5B +/+ mice

    Journal: Respiratory Research

    Article Title: MUC5B regulates goblet cell differentiation and reduces inflammation in a murine COPD model

    doi: 10.1186/s12931-021-01920-8

    Figure Lengend Snippet: MUC5B −/− mice have increased expression of macrophage-related inflammatory factors. MUC5B +/+ mice (n = 15 per group) and MUC5B −/− mice (n = 10 per group). a BAL fluid IL-6 ELISA. b BAL fluid TNF-α ELISA. c ERK1/2 western blot and grayscale analysis. d NF-κB western blot and grayscale analysis. “*” indicates a significant difference; ***P < 0.001, **P < 0.01 compared to smoke-exposed MUC5B +/+ mice

    Article Snippet: The following mouse BALF ELISA kits were used: IL-6 (DY406-05, R&D), KC (DY453-05, R&D), TNF-α (DY410-05, R&D), MUC5AC (E-EL-M0799c, Elabscience), and MUC5B (E-EL-M0800c, Elabscience).

    Techniques: Expressing, Enzyme-linked Immunosorbent Assay, Western Blot

    Changes in MPO (a1, b1), PMN elastase (a2, b2), IL-1 β (a3, b3), TNF- α (a4, b4), IL-6 (a5, b5), and IL-10 (a6, b6) levels in the serum (a) and BALF (b) from sequentially/nonsequentially treated COPD rats. AE: acute exacerbation; BYG: Bufei Yishen Granule; COPD: chronic obstructive pulmonary disease; IL: interleukin; MPO: myeloperoxidase; MXF: moxifloxacin; NS: normal saline; PMN: polymorphonuclear; RW: risk window; TNF: tumor necrosis factor; TSG: Tongsai Granule; STL: salbutamol. N = 6. ∗ P < 0.05, versus Control group; # P < 0.05, versus COPD group; ▲ P < 0.05, versus AECOPD group; ■ P < 0.05, versus TSG/NS group; □ P < 0.05, versus MXF+STL/NS group; ● P < 0.05, versus TSG/BYG group; ○ P < 0.05, versus MXF+STL/STL group.

    Journal: Evidence-based Complementary and Alternative Medicine : eCAM

    Article Title: Sequential Treatments with Tongsai and Bufei Yishen Granules Reduce Inflammation and Improve Pulmonary Function in Acute Exacerbation-Risk Window of Chronic Obstructive Pulmonary Disease in Rats

    doi: 10.1155/2016/1359105

    Figure Lengend Snippet: Changes in MPO (a1, b1), PMN elastase (a2, b2), IL-1 β (a3, b3), TNF- α (a4, b4), IL-6 (a5, b5), and IL-10 (a6, b6) levels in the serum (a) and BALF (b) from sequentially/nonsequentially treated COPD rats. AE: acute exacerbation; BYG: Bufei Yishen Granule; COPD: chronic obstructive pulmonary disease; IL: interleukin; MPO: myeloperoxidase; MXF: moxifloxacin; NS: normal saline; PMN: polymorphonuclear; RW: risk window; TNF: tumor necrosis factor; TSG: Tongsai Granule; STL: salbutamol. N = 6. ∗ P < 0.05, versus Control group; # P < 0.05, versus COPD group; ▲ P < 0.05, versus AECOPD group; ■ P < 0.05, versus TSG/NS group; □ P < 0.05, versus MXF+STL/NS group; ● P < 0.05, versus TSG/BYG group; ○ P < 0.05, versus MXF+STL/STL group.

    Article Snippet: The left BALF was centrifuged, and the supernatant was collected to determine IL-1 β , TNF- α , IL-6, IL-10, MPO, and PMN elastase levels by ELISA (Boster, Wuhan, China).

    Techniques: Saline, Control